Falcons vs. Cardinals Betting Odds, Free Picks, and Predictions - 4:05 PM ET (Sun, Dec 21, 2025)

Mon, Dec 15, 2025
NFL News (CapperTek)

The Atlanta Falcons go up against the Arizona Cardinals in NFL Football action on Sunday, December 21, 2025. Kickoff is set for 4:05 PM ET.

Need betting advice for this game? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the correct side of the betting action for this match-up.

Falcons vs. Cardinals Game Info and Betting Odds

Away Team: Atlanta Falcons (Favorite)
Home Team: Arizona Cardinals (Underdog)
Date: Sunday, December 21, 2025
Time: 4:05 PM ET
League: National Football League (NFL)

Atlanta Falcons Moneyline: -134
Arizona Cardinals Moneyline: +118

Atlanta Falcons Spread: -1.5 (-116)
Arizona Cardinals Spread: +1.5 (+102)

Game Total Points: 46 (Over -115 / Under +100)

Betting odds provided by Premium Picks. Visit PremiumPicks.com today and check out their unique wagering system that will help you beat the books! Odds and lines are the best available at the time of publishing and are subject to change.

A Closer Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both the Atlanta Falcons and the Arizona Cardinals, but let's take a closer look inside some of the betting numbers for this match-up right now.

First let's break down the away team and -134 betting favorites, the Atlanta Falcons.

In their last 10 games, the Falcons have a Straight Up record of 3 wins, 7 losses and an active Straight Up streak of 1 win in a row. Also in their last 10 games, the Falcons have an Against-the-Spread record of 4 wins, 5 losses, 1 push and an active Against-the-Spread streak of 1 win in a row. The Game Total Points results for Falcons games have a record of 6 overs, 3 unders, 1 push in their last 10 games with an active streak of 3 overs in a row.

OK now let's break down the home team and +118 betting underdogs, the Arizona Cardinals.

In their last 10 games, the Cardinals have a Straight Up record of 1 win, 9 losses and an active Straight Up streak of 6 losses in a row. Also in their last 10 games, the Cardinals have an Against-the-Spread record of 4 win, 6 losses and an active Against-the-Spread streak of 2 losses in a row. The Game Total Points results for Cardinals games have a record of 8 overs, 2 unders in their last 10 games with an active streak of 2 overs in a row.

If you want more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the Falcons vs. Cardinals Trend Finder directly.

Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

According to our simulation of the Falcons vs. Cardinals NFL game, we have the Atlanta Falcons beating the Arizona Cardinals with a simulated final score of: Atlanta Falcons [26] - Arizona Cardinals [21]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the Falcons vs. Cardinals Simulation directly. Also after the Falcons vs. Cardinals game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.

What Should I Bet On? Our Free Picks

OK let's get down to the real reason you're here, who or what should you bet on in the Falcons vs. Cardinals NFL match-up? According to the simulated prediction and results for this match-up above, we here at CapperTek suggest you place the following bets:

Free Moneyline Pick: Falcons -134

Free Spread Pick: Falcons -1.5 (-116)

Free Total Pick: Over 46 (-115)

Hopefully our free picks and predictions help you out if you're wagering on the Atlanta Falcons vs. Arizona Cardinals NFL Football match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.