Jaguars vs. Cardinals Betting Odds, Free Picks, and Predictions - 4:05 PM ET (Sun, Nov 23, 2025)

Mon, Nov 17, 2025
NFL News (CapperTek)

The Jacksonville Jaguars face-off against the Arizona Cardinals in NFL Football action on Sunday, November 23, 2025. Kickoff is set for 4:05 PM ET.

Need help deciding what to bet on? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the correct side of the betting action for this match-up.

Jaguars vs. Cardinals Game Details and Betting Odds

Away Team: Jacksonville Jaguars (Favorite)
Home Team: Arizona Cardinals (Underdog)
Date: Sunday, November 23, 2025
Time: 4:05 PM ET
League: National Football League (NFL)

Jacksonville Jaguars Moneyline: -148
Arizona Cardinals Moneyline: +129

Jacksonville Jaguars Spread: -2.5 (-114)
Arizona Cardinals Spread: +2.5 (+100)

Game Total Points: 47.5 (Over -116 / Under +100)

Betting odds provided by Premium Picks. Visit PremiumPicks.com today and check out their unique wagering system that will help you beat the books! Odds and lines are the best available at the time of publishing and are subject to change.

A Closer Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both the Jacksonville Jaguars and the Arizona Cardinals, but let's take a closer look inside some of the betting numbers for this match-up right now.

First let's take a look at the away team and -148 betting favorites, the Jacksonville Jaguars.

In their last 10 games, the Jaguars have a Straight Up record of 6 wins, 4 losses and an active Straight Up streak of 1 win in a row. Also in their last 10 games, the Jaguars have an Against-the-Spread record of 5 wins, 4 losses, 1 push and an active Against-the-Spread streak of 1 win in a row. The Game Total Points results for Jaguars games have a record of 5 overs, 5 unders in their last 10 games with an active streak of 1 under in a row.

Now let's take a look at the home team and +129 betting underdogs, the Arizona Cardinals.

In their last 10 games, the Cardinals have a Straight Up record of 3 wins, 7 losses and an active Straight Up streak of 2 losses in a row. Also in their last 10 games, the Cardinals have an Against-the-Spread record of 5 wins, 5 losses and an active Against-the-Spread streak of 2 losses in a row. The Game Total Points results for Cardinals games have a record of 6 overs, 4 unders in their last 10 games with an active streak of 2 overs in a row.

If you want more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the Jaguars vs. Cardinals Trend Finder directly.

Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

According to our simulation of the Jaguars vs. Cardinals NFL game, we have the Arizona Cardinals beating the Jacksonville Jaguars with a simulated final score of: Jacksonville Jaguars [26] - Arizona Cardinals [27]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the Jaguars vs. Cardinals Simulation directly. Also after the Jaguars vs. Cardinals game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.

What Should I Bet On? Our Free Picks

Well let's get down to the real reason you're here, who or what should you bet on in the Jaguars vs. Cardinals NFL match-up? According to the simulated prediction and results for this match-up above, we here at CapperTek suggest you make the following bets:

Free Moneyline Pick: Cardinals +129

Free Spread Pick: Cardinals +2.5 (+100)

Free Total Pick: Over 47.5 (-116)

We hope our free picks and predictions help you out if you're wagering on the Jacksonville Jaguars vs. Arizona Cardinals NFL Football match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.