The LSU Tigers and the Mississippi State Bulldogs are set to square off in an SEC matchup at 6 p.m. ET on Saturday at Tiger Stadium. The Tigers are 1-1 (1-0 at home) while MSU is 2-0 (1-0 on the road). LSU leads the all-time series with a 72-37-3 record and the Tigers won at Mississippi State last year by a 28-25 score.
The Bulldogs are favored by 2.5 points in the latest LSU vs. Mississippi State odds from Caesars Sportsbook, and the over/under is set at 53.5. Before entering any Mississippi State vs. LSU picks, you'll want to see the college football predictions and betting advice from the model at SportsLine.
The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.
Now, the model has set its sights on LSU vs. Mississippi State'and just locked in its picks and CFB predictions. You can head to SportsLine to see its picks. Here are several college football odds'and betting lines for Mississippi State vs. LSU:
- LSU vs. Mississippi State spread: LSU +2.5
- LSU vs. Mississippi State over/under: 53.5 points
- LSU vs. Mississippi State picks: See picks here
LSU Tigers vs. Mississippi State Bulldogs
Moneyline
Spread
Total
LSU
+115
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+2.5
-110
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o53
-110
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MISSST
-135
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-2.5
-110
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u53
-110
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What you need to know about LSU
When you finish with 288 more yards than your opponent like LSU did on Saturday, a favorable outcome is almost sure to follow. It took its matchup at home with ease, bagging a 65-17 victory over the Southern University Jaguars. The game was pretty much decided by the half, when the score had already reached 51-0. LSU's RB Armoni Goodwin looked sharp as he punched in two rushing touchdowns as part of an 85-yard rushing day.
Quarterback Jayden Daniels was highly efficient in completing 10-of-11 passes with three touchdowns. The Arizona State transfer is completing 77.8% of his passes on the season and also leads LSU with 132 rushing yards. But he's yet to get in sync with star receiver Kayshon Boutte as the junior has just 62 receiving yards and no touchdowns this season.
What you need to know about Mississippi State
Meanwhile, MSU took its contest against the Arizona Wildcats on Saturday by a conclusive 39-17 score. MSU QB Will Rogers was slinging it as he passed for four TDs and 302 yards on 49 attempts. It marked just the third road game for MSU against the Pac-12 and the school's first victory since 1977.
Coach Mike Leach's offense has looked as good as expected and Rogers is among the nation's leaders in several passing categories. He leads FBS in pass completions, while leading the SEC in completion percentage and passing touchdowns. Rogers threw for 371 yards, three touchdowns and one interception in last year's loss to LSU.
How to make LSU vs. Mississippi State picks
The model has simulated Mississippi State vs. LSU 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 60% of simulations. You can only see the pick at SportsLine.
So who wins LSU vs. Mississippi State? And which side of the spread hits in almost 60% of simulations?'Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.'