DukeDuke vs. LouisvilleLouisville Pick Center

Bet Now
DukeDuke 0
O 47
LouisvilleLouisville 23
U 47
FINAL (10/28/2023)

Duke vs. Louisville Betting Odds, Free Picks, and Predictions - 3:30 PM ET (Sat, Oct 28, 2023)

Duke battle Louisville in NCAA College Football action on Saturday, October 28, 2023. Kickoff is set for 3:30 PM ET.

Want betting info or a prediction for this game? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the right side of the betting action for this match-up.

Duke vs. Louisville Game Info and Betting Odds

Away Team: Duke (Underdog)
Home Team: Louisville (Favorite)
Date: Saturday, October 28, 2023
Time: 3:30 PM ET
League: NCAA College Football (NCAAF)

Duke Moneyline: +159
Louisville Moneyline: -192

Duke Spread: +4 (-109)
Louisville Spread: -4 (-109)

Game Total Points: 47 (Over -110 / Under -110)

Betting odds provided by BigBetBiz. Don't forget to check out BigBetBiz.ag if you are searching for a great book to place your sports wagers. Odds and lines are the best available at the time of publishing and are subject to change.

A Closer Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both Duke and Louisville, but let's take a closer look inside some of the betting numbers for this match-up right now.

Let's start off by breaking down the away team and +159 betting underdogs, Duke.

In their last 10 games, Duke has a Straight Up record of 7 wins, 3 losses and an active Straight Up streak of 1 loss in a row. Also in their last 10 games, Duke has an Against-the-Spread record of 7 wins, 3 losses and an active Against-the-Spread streak of 1 loss in a row. The Game Total Points results for Duke games has a record of 5 overs, 5 unders in their last 10 games with an active streak of 1 over in a row.

Now let's break down the home team and -192 betting favorites, Louisville.

In their last 10 games, Louisville has a Straight Up record of 8 wins, 2 losses and an active Straight Up streak of 1 loss in a row. Also in their last 10 games, Louisville has an Against-the-Spread record of 5 wins, 4 losses, 1 push and an active Against-the-Spread streak of 1 loss in a row. The Game Total Points results for Louisville games has a record of 4 overs, 6 unders in their last 10 games with an active streak of 1 over in a row.

If you need more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the Duke vs. Louisville Trend Finder directly.

Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

Based on our simulation of Duke vs. Louisville NCAAF game, we have Louisville beating Duke with a simulated final score of: Duke [19] - Louisville [35]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the Duke vs. Louisville Simulation directly. Also after the Duke vs. Louisville game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.

What Should I Bet On? Our Free Picks

OK let's get down to the real reason you're here, who or what should you bet on in the Duke vs. Louisville NCAAF match-up? Based on the simulated prediction and results for this match-up above, we here at CapperTek suggest you place the following bets:

Free Moneyline Pick: Louisville -192

Free Spread Pick: Louisville -4 (-109)

Free Total Pick: Over 47 (-110)

Hopefully our free picks and predictions help you out if you're wagering on the Duke vs. Louisville NCAA College Football match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.

Looking for More Picks?

You can browse all the individual handicapper picks below.

Related News (NCAAF News)

No. 18 Louisville, No. 20 Duke look to overcome losses and stay in the ACC championship picture

Thu, Oct 26, 2023

No. 18 Louisville, No. 20 Duke look to overcome losses and stay in the ACC championship picture

LOUISVILLE, Ky. (AP) - No. 18 Louisville had a week off to reset from a loss and now aims to avoid a modest skid. No. 20 Duke has the same goal, which requires finally solving the Cardinals.

Maintaining at least a piece of second place in the Atlantic Coast Conference is the mutual objective on Saturday for both teams, both of whom hope to reclaim the identities and flow that helped fuel strong starts. In the case of Louisville (6-1, 3-1 ACC), that means avoiding the freebies that surrendered a lead to Pittsburgh in a 38-21 loss that followed a milestone win over Notre Dame.

"The issue is getting refocused and dialed back in," said first-year Louisville coach Jeff Brohm, who acknowledged that it was difficult forgetting three interceptions against the Panthers, with one returned for a touchdown.

"While we got off to a good start, it means nothing. You're judged on how you do at the end of the year. We've had some tough battles and we've found ways to win close games, and I'm not guaranteeing we're going to have more. We have to make sure we dig deep as coaches and players and find a way to win all the close games we play."

Other news No. 25 James Madison's perch atop the Sun Belt's East Division on the line against Old Dominion Buffaloes try to bounce back from Cardinal implosion against No. 23 Bruins' stingy defense No. 8 Oregon clashes with no. 13 Utah in game with heavy Pac-12 title implications

Explosive plays and scoring have sparked Louisville, though it could find resistance by a Duke defense yielding just 13.9 points per game despite a 38-20 loss at No. 4 Florida State. The Blue Devils had allowed seven touchdowns through the six games amid their strong start, though they faded in the fourth quarter against the first-place Seminoles.

They nonetheless have just the one league loss and remain in the chase for a berth in the conference championship game.

"The one thing I don't question about this group is response," Duke second-year coach Mike Elko said. "I think whether we go out next week and perform well enough to get the desired result, we'll find that out on Saturday. But we're certainly going to respond the right way."


Louisville receiver Jamari Thrash posted his second 100-yard game at Pitt with nine catches for 120 yards. He has 17 receptions for 195 yards the past two games and ranks second in the ACC with 639 yards, a 91.3-yard average and six touchdowns. Louisville running back Jawhar Jordan managed just two carries for eight yards at Pitt because of injury but is listed as the starter. His 661 yards rushing and 94.4-yard average per game rank second in the ACC behind North Carolina's Omarion Hampton.


The Blue Devils continue to rank among the nation's top defenses even with giving up a season-high 38 points, a total that included a 99-yard kickoff return for a touchdown on special teams. Duke is fifth in the Bowl Subdivision ranks by allowing 13.9 points and 24th nationally in total offense at 315.9 yards per game.


Duke had a season-low 273 total yards last week, which marked the fifth straight week that the Blue Devils had a lower output than the previous game. Most of that production is coming from an effective ground game led by Jordan Waters and Jaquez Moore, but the Blue Devils are trying to get their passing game clicking again.

Dual-threat quarterback Riley Leonard grinded through an ankle injury that had sidelined him for a game before returning against FSU. But he threw for just 69 yards on 7-for-16 passing with one interception and threw for just 134 yards in the Blue Devils' first loss to Notre Dame.

"We just have to find a better rhythm, and it's at every level," Elko said, adding: "You've got to protect. You've got to make clean pockets. ... We've got to separate and get open on the perimeter. I don't think there's a magical answer to it."


Louisville sophomore Austin Collins is expected to make his second consecutive start at right guard this week in place of injured Ronato Brown, whom Brohm said this week will miss the remainder of this season with a knee injury sustained before the loss at Pitt.


The Cardinals have won all three meetings by at least 10 points, including a 40-3 win in 2002 before the Cardinals were an ACC member. The teams have met only once at Louisville (2016), and the Cardinals won the last meeting 62-22 in Durham two years ago.


AP Sports Writer Aaron Beard in Durham, North Carolina, contributed to this report.

___ Get alerts on the latest AP Top 25 poll throughout the season. Sign up here ___ AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-football

Article Copyright © 2023 The Associated Press, All Rights Reserved.
The Sports Betting Whale
The Sports Betting Whale has won over $30 Million Dollars from betting on sports. Enter your email address below to get The Whale's picks for a full month 100% FREE!
Or text "FREE" to +1 (702)-277-0282

Latest NCAAF News