Syracuse vs. Pittsburgh Pick Center

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SPREAD

TOTAL

Syracuse

+350

+11.5
(-114)

O 52
(+100)

Pittsburgh

-443

-11.5
(-104)

U 52
(-122)

NCAAF

FINAL (9/17/2026)

Syracuse vs. Pittsburgh Betting Odds, Free Picks, and Predictions - 7:30 PM ET (Thu, Sep 17, 2026)

Syracuse travel to Pittsburgh in NCAA College Football action on Thursday, September 17, 2026. Kickoff is set for 7:30 PM ET.

Thinking about betting on this game? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the winning side of the betting action for this match-up.

Syracuse vs. Pittsburgh Game Info and Betting Odds

Away Team: Syracuse (Underdog)
Home Team: Pittsburgh (Favorite)
Date: Thursday, September 17, 2026
Time: 7:30 PM ET
League: NCAA College Football (NCAAF)

Syracuse Moneyline: +333
Pittsburgh Moneyline: -453

Syracuse Spread: +12 (-122)
Pittsburgh Spread: -12 (+100)

Game Total Points: 51.5 (Over -106 / Under -121)

Betting odds provided by Premium Picks. Visit PremiumPicks.com today and check out their unique wagering system that will help you beat the books! Odds and lines are the best available at the time of publishing and are subject to change.

A Deeper Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both Syracuse and Pittsburgh, but let's take a deeper look inside some of the betting numbers for this match-up right now.

First let's take a glance at the away team and +333 betting underdogs, Syracuse.

In their last 10 games, Syracuse has a Straight Up record of 1 win, 9 losses and an active Straight Up streak of 1 loss in a row. Also in their last 10 games, Syracuse has an Against-the-Spread record of 3 win, 7 losses and an active Against-the-Spread streak of 1 loss in a row. The Game Total Points results for Syracuse games has a record of 4 overs, 6 unders in their last 10 games with an active streak of 1 under in a row.

OK now let's take a glance at the home team and -453 betting favorites, Pittsburgh.

In their last 10 games, Pittsburgh has a Straight Up record of 7 wins, 3 losses and an active Straight Up streak of 2 wins in a row. Also in their last 10 games, Pittsburgh has an Against-the-Spread record of 6 wins, 4 losses and an active Against-the-Spread streak of 1 loss in a row. The Game Total Points results for Pittsburgh games has a record of 5 overs, 5 unders in their last 10 games with an active streak of 1 under in a row.

If you need more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the Syracuse vs. Pittsburgh Trend Finder directly.

Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

Based on our simulation of Syracuse vs. Pittsburgh NCAAF game, we have Pittsburgh beating Syracuse with a simulated final score of: Syracuse [13] - Pittsburgh [45]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the Syracuse vs. Pittsburgh Simulation directly. Also after the Syracuse vs. Pittsburgh game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.

What Should I Bet On? Our Free Picks

OK let's get down to the real reason you're here, who or what should you bet on in the Syracuse vs. Pittsburgh NCAAF match-up? Based on the simulated prediction and results for this match-up above, we here at CapperTek suggest you make the following bets:

Free Moneyline Pick: Pittsburgh -453

Free Spread Pick: Pittsburgh -12 (+100)

Free Total Pick: Over 51.5 (-106)

Hopefully our free picks and predictions help you out if you're wagering on the Syracuse vs. Pittsburgh NCAA College Football match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.