Monday Night Football odds, spread, line: Titans vs. Bills predictions, NFL picks from expert who's 23-12

Mon, Sep 19, 2022
NFL News (AP)

Monday Night Football odds, spread, line: Titans vs. Bills predictions, NFL picks from expert who's 23-12

Teams with different outcomes in their season-openers will clash on Monday Night Football when the Tennessee Titans take on the Buffalo Bills. The Titans (0-1), who won the AFC South last season with a 12-5 record, stumbled in Week 1 and fell 21-20 to the New York Giants at home. The Bills (1-0), who won the AFC East at 11-6 in 2021, crushed the defending Super Bowl champion Los Angeles Rams 31-10 on the road. The Titans won last year's matchup 34-31 at Tennessee.

Kickoff from Highmark Stadium in Orchard Park, N.Y., is set for 7:15 p.m. ET. Buffalo is a 10-point favorite in the latest Titans vs. Bills odds from Caesars Sportsbook, while the over/under for total points scored is 47.5. Before making any Bills vs. Titans picks, be sure to see the NFL predictions and betting advice from SportsLine's Larry Hartstein.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed while working for Pro Football Focus. Entering the 2022 NFL season, he is 427-344 all-time on NFL sides (plus $3,764 for $100 players), including 394-330 against the spread. Hartstein went 68-50 ATS (58 percent) and 8-3 on money-line plays last season for a profit of $1,552.

In addition, Hartstein has gone 23-12-1 on his last 36 NFL picks involving the Titans, returning $1,007. Anyone who has followed him is way up.

Now, Hartstein has set his sights on Titans vs. Bills and locked in his NFL picks and predictions. You can head to SportsLine to see his picks. Here are several NFL odds and trends for Bills vs. Titans:

  • Titans vs. Bills spread: Buffalo -10
  • Titans vs. Bills over-under: 47.5 points
  • Titans vs. Bills money line: Tennessee +360, Buffalo -480
  • TEN: Titans are 8-2 against the spread in their last 10 Monday games
  • BUF: Bills are 4-0-1 ATS in their last five games as favorites
  • Titans vs. Bills picks: See picks at SportsLine
Buffalo Bills vs. Tennessee Titans Moneyline Spread Total BUF -480 BET NOW -10 -110 BET NOW o47.5 -110 BET NOW TEN +360 BET NOW +10 -110 BET NOW u47.5 -110 BET NOW

Why the Bills can cover

Buffalo quarterback Josh Allen'completed 26 of 31 attempts (83.9%) for 297 yards and three touchdowns against the Rams last week. He also rushed for 56 yards and a touchdown, his seventh-career game with three-plus TD passes and a rushing touchdown, which is third-most all-time. He had two or more touchdown passes in six of nine home games last season. In the last meeting against the Titans, Allen passed for 353 yards and three touchdowns with an interception for a 107.8 rating.

Also leading the Buffalo offense is veteran wide receiver Stefon Diggs. He led the Bills with eight catches for 122 yards and one touchdown in last week's victory over Los Angeles. It was his 10th game with 100 or more receiving yards since joining Buffalo in 2020. He has 298 receiving yards (99.3 per game) in three career games against the Titans.

Why the Titans can cover

Tennessee will try to rebound behind quarterback Ryan Tannehill, who completed 20 of 33 passes (60.6%) for 266 yards and two touchdowns last week. Tannehill will look for his fifth regular season game in a row with zero interceptions and a 105-plus rating and fourth in a row with two or more TD passes. He had 13 touchdowns, including 11 passing, against five interceptions for a 92.6 rating in eight road starts last season.

Also powering the Titans is running back Derrick Henry, who rushed for 82 yards in Week 1. Henry has 75 or more yards from scrimmage in 12 of his past 1 games, and rushed for 143 yards and three touchdowns in the last meeting against Buffalo. He totaled 612 scrimmage yards (153 per game) and seven rushing TDs in four road games last season.

How to make Bills vs. Titans picks

Hartstein has analyzed this matchup from every angle and while we can tell you he's leaning Over the total, he has discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and who to back, at SportsLine.

So who wins Bills vs. Titans on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Bills vs. Titans spread to back, all from the NFL expert who's 23-12 on picks involving Tennessee, and find out.

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