NFL odds, lines, picks, spreads, best bets, predictions for Week 2, 2022: Model backing Browns and Cardinals

Sun, Sep 18, 2022
NFL News (AP)

The New York Giants opened the season with an encouraging performance, using a late touchdown to upset Tennessee. They will try to back up that victory when they host Carolina on Sunday during the Week 2 NFL schedule. Caesars Sportsbook lists the Giants listed as 2-point favorites in the latest Week 2 NFL odds, while the total is 43. Some of the other intriguing Week 2 NFL spreads include the Ravens as 3.5-point favorites against the Dolphins and the Buccaneers as 2.5-point road favorites at New Orleans. Which NFL matchups should be included in your Week 2 NFL bets? All of the Week 2 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 2 NFL picks now.'

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception. The model enters the 2022 NFL season on an incredible 139-98 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of AP Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 2 NFL odds from Caesars and locked in picks for every NFL matchup. Head here to see every pick.

One of the model's strongest Week 2 NFL picks is that the Browns (-6.5) cover at home against the Jets. Cleveland desperately needed to get off to a strong start this season following the Deshaun Watson drama in the offseason, and the Browns were able to accomplish that goal with a 26-24 win over Carolina in Week 1. Backup quarterback Jacoby Brissett threw for just 147 yards on 34 passes, but running back Nick Chubb rushed 22 times for 141 yards.

Second-string back Kareem Hunt added 46 rushing yards on 11 carries and will now face a Jets defense that ranked No. 29 in the NFL against the run last year. Chubb and Hunt combine for more than 120 rushing yards in the model's latest simulations, while Brissett is throwing a pair of touchdowns. The Jets are 1-7 in their last eight road games, one reason why the Browns cover the spread almost 60% of the time.'See who else to back here.

Another one of its Week 2 NFL predictions: The Cardinals (+5.5) cover the spread on the road versus the Raiders. Vegas signed Chandler Jones, the Cardinals' franchise leader in sacks, in the offseason, but the Raiders were the only team in Week 1 that failed to record either a sack or a takeaway.

Las Vegas lost on the field and failed to cover against Los Angeles as underdogs. It hasn't had any more success as recent favorites, as the Raiders have failed to cover their last nine games laying points. That's the longest streak by any team since the Falcons in 2015-16. SportsLine's model acknowledges the Raiders' futility as favorites as well as the Cardinals' efficacy on the road. Last year, Arizona went 8-1 ATS on the road, so escaping its home stadium may do the team some good. The model projects just a two-point game, so the Cards (+5.5) cover in almost 60 percent of simulations.'See which other teams to pick here.

The model has also made the call on who wins and covers in every other game on the Week 2 NFL schedule, and it's calling for a Super Bowl contender to go down hard.'You can only get every pick for every game at SportsLine.

So what NFL picks can you make with confidence? And which Super Bowl contender goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned over $7,500 since its inception, and find out.

Get full NFL picks at SportsLine

Sunday, Sept. 18

Dolphins at Ravens (-3.5, 44)

Baltimore Ravens vs. Miami Dolphins Moneyline Spread Total BAL -180 BET NOW -3.5 -110 BET NOW o44 -110 BET NOW MIA +152 BET NOW +3.5 -110 BET NOW u44 -110 BET NOW

Jets at Browns (-6.5, 38.5)

Cleveland Browns vs. New York Jets Moneyline Spread Total CLE -278 BET NOW -6.5 -110 BET NOW o38.5 -110 BET NOW NYJ +222 BET NOW +6.5 -110 BET NOW u38.5 -110 BET NOW

Colts at Jaguars (+3, 43.5)

Jacksonville Jaguars vs. Indianapolis Colts Moneyline Spread Total JAC +140 BET NOW +3 -110 BET NOW o43.5 -110 BET NOW IND -165 BET NOW -3 -110 BET NOW u43.5 -110 BET NOW

Buccaneers at Saints (+2.5, 43.5)

New Orleans Saints vs. Tampa Bay Buccaneers Moneyline Spread Total NO +118 BET NOW +2.5 -110 BET NOW o43.5 -110 BET NOW TB -140 BET NOW -2.5 -110 BET NOW u43.5 -110 BET NOW

Panthers at Giants (PK, 43.5)

New York Giants vs. Carolina Panthers Moneyline Spread Total NYG -110 BET NOW PK -110 BET NOW o43.5 -110 BET NOW CAR -110 BET NOW PK -110 BET NOW u43.5 -110 BET NOW

Patriots at Steelers (+3, 40.5)

Pittsburgh Steelers vs. New England Patriots Moneyline Spread Total PIT +130 BET NOW +3 -110 BET NOW o40.5 -110 BET NOW NE -155 BET NOW -3 -110 BET NOW u40.5 -110 BET NOW

Commanders at Lions (PK, 48.5)

Detroit Lions vs. Washington Commanders Moneyline Spread Total DET -110 BET NOW PK -110 BET NOW o48.5 -110 BET NOW WAS -110 BET NOW PK -110 BET NOW u48.5 -110 BET NOW

Seahawks at 49ers (-9, 39.5)

San Francisco 49ers vs. Seattle Seahawks Moneyline Spread Total SF -430 BET NOW -9 -110 BET NOW o39.5 -110 BET NOW SEA +328 BET NOW +9 -110 BET NOW u39.5 -110 BET NOW

Falcons at Rams (-10, 46)

Los Angeles Rams vs. Atlanta Falcons Moneyline Spread Total LAR -550 BET NOW -10 -110 BET NOW o46 -110 BET NOW ATL +400 BET NOW +10 -110 BET NOW u46 -110 BET NOW

Texans at Broncos (-10, 45.5)

Denver Broncos vs. Houston Texans Moneyline Spread Total DEN -480 BET NOW -10 -110 BET NOW o45.5 -110 BET NOW HOU +360 BET NOW +10 -110 BET NOW u45.5 -110 BET NOW

Cardinals at Raiders (-5.5, 51.5)

Las Vegas Raiders vs. Arizona Cardinals Moneyline Spread Total LV -235 BET NOW -5.5 -110 BET NOW o51.5 -110 BET NOW ARI +192 BET NOW +5.5 -110 BET NOW u51.5 -110 BET NOW

Bengals at Cowboys (+7, 41.5)

Dallas Cowboys vs. Cincinnati Bengals Moneyline Spread Total DAL +270 BET NOW +7 -110 BET NOW o42 -110 BET NOW CIN -345 BET NOW -7 -110 BET NOW u42 -110 BET NOW

Bears at Packers (-10, 42)

Green Bay Packers vs. Chicago Bears Moneyline Spread Total GB -480 BET NOW -10 -110 BET NOW o42 -110 BET NOW CHI +360 BET NOW +10 -110 BET NOW u42 -110 BET NOW

Monday, Sept. 19

Titans at Bills (-10, 47.5)

Buffalo Bills vs. Tennessee Titans Moneyline Spread Total BUF -480 BET NOW -10 -110 BET NOW o47.5 -110 BET NOW TEN +360 BET NOW +10 -110 BET NOW u47.5 -110 BET NOW

Vikings at Eagles (-2.5, 50.5)

Philadelphia Eagles vs. Minnesota Vikings Moneyline Spread Total PHI -135 BET NOW -2.5 -110 BET NOW o50.5 -110 BET NOW MIN +115 BET NOW +2.5 -110 BET NOW u50.5 -110 BET NOW