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Northern Illinois vs. Mississippi State Betting Odds, Free Picks, and Predictions - 4:15 PM ET (Sat, Sep 20, 2025)


Northern Illinois take on Mississippi State in NCAA College Football action on Saturday, September 20, 2025. Kickoff is set for 4:15 PM ET.

Need betting advice for this game? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the winning side of the betting action for this match-up.


Northern Illinois vs. Mississippi State Game Details and Betting Odds

Away Team: Northern Illinois (Underdog)
Home Team: Mississippi State (Favorite)
Date: Saturday, September 20, 2025
Time: 4:15 PM ET
League: NCAA College Football (NCAAF)

Northern Illinois Moneyline: +932
Mississippi State Moneyline: -1924

Northern Illinois Spread: +22 (-105)
Mississippi State Spread: -22 (-113)

Game Total Points: 50 (Over -114 / Under -108)

Betting odds provided by Premium Picks. Visit PremiumPicks.com today and check out their unique wagering system that will help you beat the books! Odds and lines are the best available at the time of publishing and are subject to change.


A Deeper Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both Northern Illinois and Mississippi State, but let's take a deeper look inside some of the betting numbers for this match-up right now.

First let's take a glance at the away team and +932 betting underdogs, Northern Illinois.

In their last 10 games, Northern Illinois has a Straight Up record of 6 wins, 4 losses and an active Straight Up streak of 1 loss in a row. Also in their last 10 games, Northern Illinois has an Against-the-Spread record of 4 wins, 6 losses and an active Against-the-Spread streak of 1 win in a row. The Game Total Points results for Northern Illinois games has a record of 4 overs, 6 unders in their last 10 games with an active streak of 2 unders in a row.

OK now let's take a glance at the home team and -1924 betting favorites, Mississippi State.

In their last 10 games, Mississippi State has a Straight Up record of 4 wins, 6 losses and an active Straight Up streak of 3 wins in a row. Also in their last 10 games, Mississippi State has an Against-the-Spread record of 8 wins, 2 losses and an active Against-the-Spread streak of 4 wins in a row. The Game Total Points results for Mississippi State games has a record of 6 overs, 4 unders in their last 10 games with an active streak of 1 over in a row.

If you want more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the Northern Illinois vs. Mississippi State Trend Finder directly.


Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

Based on our simulation of Northern Illinois vs. Mississippi State NCAAF game, we have Mississippi State beating Northern Illinois with a simulated final score of: Northern Illinois [6] - Mississippi State [38]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the Northern Illinois vs. Mississippi State Simulation directly. Also after the Northern Illinois vs. Mississippi State game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.


What Should I Bet On? Our Free Picks

Well let's get down to the real reason you're here, who or what should you bet on in the Northern Illinois vs. Mississippi State NCAAF match-up? Based on the simulated prediction and results for this match-up above, we here at CapperTek suggest you make the following bets:

Free Moneyline Pick: Mississippi State -1924

Free Spread Pick: Mississippi State -22 (-113)

Free Total Pick: Under 50 (-108)


Hopefully our free picks and predictions help you out if you're wagering on the Northern Illinois vs. Mississippi State NCAA College Football match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.

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