Syracuse Orange vs Clemson Tigers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Memorial Stadium is the location where the Clemson Tigers (1-2) will attempt to beat the Syracuse Orange (2-1) on Saturday, September 20, 2025. Syracuse opens as 17.0-point underdogs. The total has been set at 55.5. We have included an expert college football pick and parlay for todays game against the spread. Read Full Article

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Tulane Green Wave vs Ole Miss Rebels Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Tulane Green Wave (2-0) are hitting the road to Vaught-Hemingway Stadium on Saturday, September 20, 2025 where they will attempt to beat the Ole Miss Rebels (3-0). Ole Miss opens as 12.0-point favorites. The over/under is set at 61.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread. Read Full Article

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Bowling Green Falcons vs Louisville Cardinals Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

L&N Federal Credit Union Stadium is the location where the Louisville Cardinals (2-0) will attempt to beat the Bowling Green Falcons (2-1) on Saturday, September 20, 2025. Louisville opens as 26.5-point favorites. The betting total is set at 51.5. This report has odds and your NCAA football predictions for todays game against the spread. Read Full Article

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Maryland Terrapins vs Wisconsin Badgers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Maryland Terrapins (3-0) are en route to Camp Randall Stadium on Saturday, September 20, 2025 where they will take on the Wisconsin Badgers (2-1). Maryland is 8.5-point underdogs from Vegas oddsmakers. The over/under is set at 43.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight. Read Full Article

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Troy Trojans vs Buffalo Bulls Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Buffalo Bulls (2-1) will try to beat the Troy Trojans (1-2) at UB Stadium on Saturday, September 20, 2025. Buffalo opens this game as 6.0-point favorites. The total comes in at 42. This matchup report has your NCAA football pick of the day as well as college football odds for the game. Read Full Article

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Louisiana Ragin' Cajuns vs Eastern Michigan Eagles Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Louisiana Ragin' Cajuns (1-2) are on their way to Rynearson Stadium on Saturday, September 20, 2025 where they will try to defeat the Eastern Michigan Eagles (0-3). Louisiana opens this contest as 3.0-point favorites from oddsmakers. The betting total comes in at 52. This games report has current odds, betting predictions, and free picks against the spread. Read Full Article

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Georgia State Panthers vs Vanderbilt Commodores Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

FirstBank Stadium is the site where the Vanderbilt Commodores (3-0) will take on the Georgia State Panthers (1-2) on Saturday, September 20, 2025. Georgia State opens this game as 26.5-point underdogs. The total is 53.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner. Read Full Article

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NIU Huskies vs Mississippi State Bulldogs Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Mississippi State Bulldogs (3-0) will play the NIU Huskies (1-1) at Davis Wade Stadium on Saturday, September 20, 2025. Mississippi State is 21.5-point favorites. The over/under is 50. This matchup report includes Vegas odds and a free NCAA football pick for tonight. Read Full Article

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UNLV Rebels vs Miami RedHawks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The UNLV Rebels (3-0) are headed to Yager Stadium on Saturday, September 20, 2025 where they will try to defeat the Miami RedHawks (0-2). Miami opens this contest as 2.5-point dogs. The total comes in at 49. This matchup report includes Vegas odds and a free college football prediction for tonight. Read Full Article

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Sam Houston Bearkats vs Texas Longhorns Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Sam Houston Bearkats (0-3) are en route to DKR-Texas Memorial Stadium on Saturday, September 20, 2025 where they will try to defeat the Texas Longhorns (2-1). Sam Houston is 41.0-point dogs from oddsmakers. The total comes in at 51.5. This report has odds and your NCAA football predictions for todays game against the spread. Read Full Article

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Fresno State Bulldogs vs Hawaii Warriors Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Clarence T.C. Ching Athletics Complex is the location where the Hawaii Warriors (2-1) will try to beat the Fresno State Bulldogs (2-1) on Saturday, September 20, 2025. Fresno State opens this matchup as 3.0-point favorites. The betting total comes in at 47.5. This matchup report includes Vegas odds and a free NCAA football pick for tonight. Read Full Article

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California Golden Bears vs San Diego State Aztecs Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Snapdragon Stadium is where the San Diego State Aztecs (1-1) will take on the California Golden Bears (2-0) on Saturday, September 20, 2025. California opens this game as 13.0-point favorites. The betting total is set at 48.5. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup. Read Full Article

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Boise State Broncos vs Air Force Falcons Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Boise State Broncos (1-1) are hitting the road to Falcon Stadium on Saturday, September 20, 2025 where they will attempt to defeat the Air Force Falcons (1-0). Air Force opens this matchup as 10.0-point underdogs. The over/under is 51.5. This matchup report includes Vegas odds and a free college football prediction for tonight. Read Full Article

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Ball State Cardinals vs Connecticut Huskies Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Pratt & Whitney Stadium is the site where the Connecticut Huskies (1-2) will try to defeat the Ball State Cardinals (1-2) on Saturday, September 20, 2025. Ball State is 20.5-point dogs. The total comes in at 52.5. This matchup report includes betting lines and our NCAA football pick of the day for this game. Read Full Article

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Washington Huskies vs Washington State Cougars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Washington Huskies (2-0) are en route to Martin Stadium on Saturday, September 20, 2025 where they will attempt to defeat the Washington State Cougars (2-1). Washington opens this matchup as 20.0-point favorites from oddsmakers. The total is set at 53. This matchup report has your NCAA football pick of the day as well as college football odds for the game. Read Full Article

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Arkansas State Red Wolves vs Kennesaw State Owls Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Arkansas State Red Wolves (1-2) are en route to Fifth Third Stadium on Saturday, September 20, 2025 where they will try to defeat the Kennesaw State Owls (1-2). Kennesaw State opens as 6.0-point underdogs. The betting total is set at 54.5. This matchup report includes odds, betting predictions and a free pick against the spread. Read Full Article

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Nevada Wolf Pack vs Western Kentucky Hilltoppers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Nevada Wolf Pack (1-2) are en route to Houchens Industries on Saturday, September 20, 2025 where they will attempt to defeat the Western Kentucky Hilltoppers (2-1). Western Kentucky opens this contest as 10.5-point favorites. The total comes in at 55.5. This games report has current odds, betting predictions, and free picks against the spread. Read Full Article

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UAB Blazers vs Tennessee Volunteers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Tennessee Volunteers (2-1) will compete against the UAB Blazers (1-1) at Neyland Stadium on Saturday, September 20, 2025. UAB is 39.0-point underdogs. The total has been set at 67. This matchup report includes Vegas odds and a free NCAA football pick for tonight. Read Full Article

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Purdue Boilermakers vs Notre Dame Fighting Irish Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Purdue Boilermakers (2-1) are on their way to Notre Dame Stadium on Saturday, September 20, 2025 where they will meet the Notre Dame Fighting Irish (0-1). Notre Dame opens this game as 27.0-point favorites from oddsmakers. The total is 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread. Read Full Article

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North Texas Mean Green vs Army Black Knights Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Army Black Knights (1-1) host the North Texas Mean Green (3-0) at Michie Stadium on Saturday, September 20, 2025. North Texas opens this contest as 1.0-point dogs. The betting total comes in at 52. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup. Read Full Article

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Michigan Wolverines vs Nebraska Cornhuskers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Memorial Stadium is the location where the Nebraska Cornhuskers (3-0) will take on the Michigan Wolverines (2-1) on Saturday, September 20, 2025. Michigan opens this game as 2.5-point favorites. The over/under is 45. This report includes betting odds and our expert football picks for todays game. Read Full Article

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James Madison Dukes vs Liberty Flames Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Liberty Flames (1-2) will compete against the James Madison Dukes (1-1) at Williams Stadium on Saturday, September 20, 2025. Liberty opens this contest as 10.0-point dogs. The total has been set at 49. This report includes betting odds and our expert football picks for todays game. Read Full Article

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West Virginia Mountaineers vs Kansas Jayhawks Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Kansas Jayhawks (2-1) will take on the West Virginia Mountaineers (2-1) at David Booth Kansas Memorial Stadium on Saturday, September 20, 2025. West Virginia opens this game as 11.5-point underdogs. The total comes in at 55.5. This matchup report includes odds, NCAA football betting predictions and a free pick against the spread. Read Full Article

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Toledo Rockets vs Western Michigan Broncos Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Western Michigan Broncos (0-3) will compete against the Toledo Rockets (2-1) at Waldo Stadium on Saturday, September 20, 2025. Western Michigan opens this game as 14.0-point underdogs. The betting total comes in at 50.5. This report has odds and your NCAA football predictions for todays game against the spread. Read Full Article

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Marshall Thundering Herd vs MTSU Blue Raiders Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Marshall Thundering Herd (1-2) are en route to Johnny "Red" Floyd Stadium on Saturday, September 20, 2025 where they will play the MTSU Blue Raiders (1-2). Marshall opens this contest as 2.5-point favorites. The total is 47. This matchup report includes betting lines and our NCAA football pick of the day for this game. Read Full Article

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UL Monroe Warhawks vs UTEP Miners Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The UL Monroe Warhawks (1-1) are on their way to Sun Bowl on Saturday, September 20, 2025 where they will meet the UTEP Miners (1-2). UTEP opens this game as 5.0-point favorites. The total comes in at 47. This matchup report includes Vegas odds and a free NCAA football pick for tonight. Read Full Article

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Coastal Carolina Chanticleers vs South Alabama Jaguars Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Hancock Whitney Stadium is the location where the South Alabama Jaguars (1-2) will attempt to defeat the Coastal Carolina Chanticleers (1-2) on Saturday, September 20, 2025. South Alabama opens as 14.5-point favorites from Vegas oddsmakers. The betting total is set at 50.5. This matchup report has Vegas lines and an expert college football football pick for your daily winner. Read Full Article

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UTSA Roadrunners vs Colorado State Rams Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Colorado State Rams (1-1) will try to beat the UTSA Roadrunners (1-2) at Canvas Stadium on Saturday, September 20, 2025. Colorado State opens this contest as 4.5-point dogs. The over/under is set at 59.5. This matchup report includes odds, betting predictions and a free pick against the spread. Read Full Article

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NC State Wolfpack vs Duke Blue Devils Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

Wallace Wade Stadium is the site where the Duke Blue Devils (1-1) will try to defeat the NC State Wolfpack (3-0) on Saturday, September 20, 2025. Duke opens as 3.5-point favorites. The over/under has been set at 58. This matchup report includes Vegas odds and a free college football prediction for tonight. Read Full Article

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Arkansas Razorbacks vs Memphis Tigers Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Memphis Tigers (3-0) welcome the Arkansas Razorbacks (2-1) at Simmons Bank Liberty Stadium on Saturday, September 20, 2025. Arkansas opens this contest as 7.5-point favorites from Vegas oddsmakers. The betting total comes in at 62.5. This matchup report includes betting lines and our NCAA football pick of the day for this game. Read Full Article

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Wyoming Cowboys vs Colorado Buffaloes Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Wyoming Cowboys (2-1) are on their way to Folsom Field on Saturday, September 20, 2025 where they will take on the Colorado Buffaloes (1-2). Wyoming opens this contest as 13.0-point dogs. The over/under is set at 44. This game report has an NCAA football pick, betting odds, and predictions for tonights key matchup. Read Full Article

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Michigan State Spartans vs USC Trojans Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Michigan State Spartans (3-0) are on their way to Los Angeles Memorial Coliseum on Saturday, September 20, 2025 where they will try to beat the USC Trojans (3-0). Michigan State opens this game as 17.0-point dogs. The betting total comes in at 56. This matchup report includes odds, betting predictions and a free pick against the spread. Read Full Article

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BYU Cougars vs East Carolina Pirates Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The East Carolina Pirates (2-1) will compete against the BYU Cougars (2-0) at Dowdy-Ficklen Stadium on Saturday, September 20, 2025. BYU opens this matchup as 7.5-point favorites. The betting total comes in at 48. This matchup report includes Vegas odds and a free NCAA football pick for tonight. Read Full Article

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Temple Owls vs Georgia Tech Yellow Jackets Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The Georgia Tech Yellow Jackets (3-0) will try to beat the Temple Owls (2-1) at Bobby Dodd Stadium on Saturday, September 20, 2025. Georgia Tech opens this contest as 24.0-point favorites. The over/under comes in at 52. This matchup report has Vegas lines and an expert college football football pick for your daily winner. Read Full Article

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North Carolina Tar Heels vs UCF Knights Prediction, 9/20/2025 College Football Picks, Best Bets & Odds

The North Carolina Tar Heels (2-1) are hitting the road to FBC Mortgage Stadium on Saturday, September 20, 2025 where they will meet the UCF Knights (2-0). UCF opens this matchup as 6.5-point favorites from oddsmakers. The betting total is set at 49. This matchup report has your NCAA football pick of the day as well as college football odds for the game. Read Full Article

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