Cleveland GuardiansCleveland Guardians vs. Chicago White SoxChicago White Sox Pick Center

ML SPREAD TOTAL
Cleveland GuardiansCleveland Guardians 4
-155
-1.5
(+120)
O 7
(-115)
Chicago White SoxChicago White Sox 2
+135
+1.5
(-140)
U 7
(-105)
MLBMLB
FINAL (9/22/2022)

Guardians vs. White Sox Betting Odds, Free Picks, and Predictions - 8:10 PM ET (Thu, Sep 22, 2022)


The Cleveland Guardians take on the Chicago White Sox in MLB Baseball action on Thursday, September 22, 2022. First pitch is set for 8:10 PM ET.

Are you looking to bet on this game? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the right side of the betting action for this match-up.


Guardians vs. White Sox Game Info and Betting Odds

Away Team: Cleveland Guardians (Favorite)
Home Team: Chicago White Sox (Underdog)
Date: Thursday, September 22, 2022
Time: 8:10 PM ET
League: Major League Baseball (MLB)

Cleveland Guardians Moneyline: -135
Chicago White Sox Moneyline: +115

Cleveland Guardians Run Line: -1.5 (+130)
Chicago White Sox Run Line: +1.5 (-150)

Game Total Runs: 7 (Over -125 / Under +105)

Betting odds provided by DraftKings. Make sure you check out DraftKings Sportsbook if you need a great reliable book to place your sports wagers. Odds and lines are the best available at the time of publishing and are subject to change.


A Closer Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both the Cleveland Guardians and the Chicago White Sox, but let's take a closer look inside some of the betting numbers for this match-up right now.

First let's take a look at the away team and -135 betting favorites, the Cleveland Guardians.

In their last 10 games, the Guardians have a Straight Up record of 8 wins, 2 losses and an active Straight Up streak of 3 wins in a row. Also in their last 10 games, the Guardians have an Against-the-Spread record of 6 wins, 4 losses and an active Against-the-Spread streak of 3 wins in a row. The Game Total Runs results for Guardians games have a record of 6 overs, 4 unders in their last 10 games with an active streak of 3 overs in a row.

Now let's take a look at the home team and +115 betting underdogs, the Chicago White Sox.

In their last 10 games, the White Sox have a Straight Up record of 5 wins, 5 losses and an active Straight Up streak of 2 losses in a row. Also in their last 10 games, the White Sox have an Against-the-Spread record of 4 wins, 6 losses and an active Against-the-Spread streak of 2 losses in a row. The Game Total Runs results for White Sox games have a record of 6 overs, 4 unders in their last 10 games with an active streak of 3 overs in a row.

If you want more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the Guardians vs. White Sox Trend Finder directly.


Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

Based on our simulation of the Guardians vs. White Sox MLB game, we have the Cleveland Guardians beating the Chicago White Sox with a simulated final score of: Cleveland Guardians [7] - Chicago White Sox [3]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the Guardians vs. White Sox Simulation directly. Also after the Guardians vs. White Sox game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.


What Should I Bet On? Our Free Picks

Well let's get down to the real reason you're here, who or what should you bet on in the Guardians vs. White Sox MLB match-up? Based on the simulated prediction and results for this match-up above, we here at CapperTek suggest you make the following bets:

Free Moneyline Pick: Guardians -135

Free Run Line Pick: Guardians -1.5 (+130)

Free Total Pick: Over 7 (-125)


We hope our free picks and predictions help you out if you're wagering on the Cleveland Guardians vs. Chicago White Sox MLB Baseball match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.

Looking for More Picks?

You can browse all the individual handicapper picks below.

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Related News (MLB News)

Bieber wins again as Guardians beat White Sox 4-2 for sweep

Thu, Sep 22, 2022
MLB News (AP)

Bieber wins again as Guardians beat White Sox 4-2 for sweep

CHICAGO (AP) - Shane Bieber pitched two-run ball into the eighth inning, and the Cleveland Guardians beat the Chicago White Sox 4-2 on Thursday night for a three-game series sweep.

Cleveland opened a seven-game lead over Chicago in the AL Central with its 15th win in 18 games. The Guardians (83-67) can clinch the franchise's first division title since 2018 as early as Sunday.

Bieber (12-8) earned his fourth straight win. The 2020 AL Cy Young Award winner allowed seven hits, struck out five and walked none in 7 2/3 innings.

Trevor Stephan finished the eighth and Emmanuel Clase handled the ninth for his AL-best 37th save in 41 chances.

Gavin Sheets homered for Chicago in the eighth. Johnny Cueto (7-9) allowed four runs, three earned, and eight hits in six innings in his third straight loss.

The White Sox (76-74) have dropped three straight and four of six overall.

Cleveland went ahead to stay on Jose Ramirez's sacrifice fly in the third. Steven Kwan hit an RBI triple in the fifth and scored on another Ramirez sacrifice fly, giving the Guardians a 4-1 lead.

The White Sox, who started September with an 8-2 streak but failed to make up much ground on the streaking Guardians, got a run in the first on Eloy Jimenez's RBI single.

  • BAD THROW

    The Guardians' second run was set up by a Cueto pickoff attempt that bounced in front of first baseman Jose Abreu's glove in the third. The ball rolled to the dugout fence and allowed Amed Rosario to dash from first to third. He came home a pitch later on Ramirez's sacrifice fly.

    TRAINER'S ROOM

    Guardians: RHP Zach Plesac (broken finger) could get a start or two before the end of the season, but manager Terry Francona said it only will happen if Plesac is ready. He has been out since Aug. 30.

    UP NEXT

    Guardians: Cody Morris (0-2, 2.30 ERA) faces Texas right-hander Jon Gray (7-7, 3.80 ERA) on Friday night.

    White Sox: RHP Lucas Giolito (10-9, 5.07 ERA) goes against Tigers LHP Eduardo Rodriguez (3-5, 4.35 ERA) on Friday night.

    Article Copyright © 2022 The Associated Press, All Rights Reserved.
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