San Francisco 49ersSan Francisco 49ers vs. Denver BroncosDenver Broncos Pick Center

ML SPREAD TOTAL
San Francisco 49ersSan Francisco 49ers 10
-120
-1.5
(-110)
O 44.5
(-110)
Denver BroncosDenver Broncos 11
+100
+1.5
(-110)
U 44.5
(-110)
NFLNFL
FINAL (9/25/2022)

49ers vs. Broncos Betting Odds, Free Picks, and Predictions - 8:20 PM ET (Sun, Sep 25, 2022)


The San Francisco 49ers take on the Denver Broncos in NFL Football action on Sunday, September 25, 2022. Kickoff is set for 8:20 PM ET.

Are you looking to bet on this game? You've found the right article! We at CapperTek have all the latest sports betting tools and information to help put you on the right side of the betting action for this match-up.


49ers vs. Broncos Game Info and Betting Odds

Away Team: San Francisco 49ers (Underdog)
Home Team: Denver Broncos (Favorite)
Date: Sunday, September 25, 2022
Time: 8:20 PM ET
League: National Football League (NFL)

San Francisco 49ers Moneyline: +115
Denver Broncos Moneyline: -135

San Francisco 49ers Spread: +2 (-110)
Denver Broncos Spread: -2 (-110)

Game Total Points: 43 (Over -110 / Under -110)

Betting odds provided by DraftKings. Make sure you check out DraftKings Sportsbook if you need a great reliable book to place your sports wagers. Odds and lines are the best available at the time of publishing and are subject to change.


A Closer Look Inside the Betting Numbers

We here at CapperTek provide in-depth betting trends for both the San Francisco 49ers and the Denver Broncos, but let's take a closer look inside some of the betting numbers for this match-up right now.

First let's take a look at the away team and +115 betting underdogs, the San Francisco 49ers.

In their last 10 games, the 49ers have a Straight Up record of 7 wins, 3 losses and an active Straight Up streak of 1 win in a row. Also in their last 10 games, the 49ers have an Against-the-Spread record of 8 wins, 2 losses and an active Against-the-Spread streak of 1 win in a row. The Game Total Points results for 49ers games have a record of 1 over, 8 unders, 1 pushes in their last 10 games with an active streak of 5 unders in a row.

Now let's take a look at the home team and -135 betting favorites, the Denver Broncos.

In their last 10 games, the Broncos have a Straight Up record of 3 wins, 7 losses and an active Straight Up streak of 1 win in a row. Also in their last 10 games, the Broncos have an Against-the-Spread record of 3 wins, 7 losses and an active Against-the-Spread streak of 2 losses in a row. The Game Total Points results for Broncos games have a record of 3 overs, 7 unders in their last 10 games with an active streak of 2 unders in a row.

If you want more detailed betting information for this match-up such as the trends or steaks broken down into Home vs. Away splits, or Favorite vs. Underdog splits, make sure to check out the 49ers vs. Broncos Trend Finder directly.


Who's Going to Win This Game? Our Prediction

We pride ourselves here at CapperTek on providing our users with the most advanced machine learning artificial intelligence to simulate game outcomes using algorithms we have custom designed over 10+ years of research and development.

Based on our simulation of the 49ers vs. Broncos NFL game, we have the San Francisco 49ers beating the Denver Broncos with a simulated final score of: San Francisco 49ers [20] - Denver Broncos [17]

Sometimes our game simulations change, like if there's a major line movement, drastic shift in the odds, or if there's a key injury, etc. To make sure you have the latest and most accurate simulation, you can run the 49ers vs. Broncos Simulation directly. Also after the 49ers vs. Broncos game is finished, you can re-run the simulation and check out how the simulated final result did compared to the actual final result.


What Should I Bet On? Our Free Picks

Well let's get down to the real reason you're here, who or what should you bet on in the 49ers vs. Broncos NFL match-up? Based on the simulated prediction and results for this match-up above, we here at CapperTek suggest you make the following bets:

Free Moneyline Pick: 49ers +115

Free Spread Pick: 49ers +2 (-110)

Free Total Pick: Under 43 (-110)


We hope our free picks and predictions help you out if you're wagering on the San Francisco 49ers vs. Denver Broncos NFL Football match-up. Our betting tips are based on detailed analytics and wagering intelligence to provide you the best possible plays. Our goal is to provide valuable sports betting information to gamblers and help put them on the right side of the action.

Please remember to always wager responsibly. For problem gambling help, please visit the National Council on Problem Gambling.

This article was generated using CapperTek's Betelligence Publisher API. Learn more.

Looking for More Picks?

You can browse all the individual handicapper picks below.

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Related News (NFL News)

Broncos' Hackett hires Rosburg to help him in his decisions

Sun, Sep 25, 2022
NFL News (AP)

Broncos' Hackett hires Rosburg to help him in his decisions

DENVER (AP) - Denver Broncos first-year head coach Nathaniel Hackett has lured longtime NFL assistant coach Jerry Rosburg out of retirement to help him make better decisions during games.

Rosburg, 66, agreed to join Hackett's staff after observing practice during the week and meeting with quarterback Russell Wilson and others in the organization.

His first game in the booth for the Broncos (1-1) came Sunday night against the San Francisco 49ers (1-1).

Rosburg's hiring as a senior assistant followed several operational miscues by Denver's rookie head coach and multiple communication breakdowns on his staff in the first two weeks of the season.

Hackett said a day after Denver's 16-9 win over Houston last weekend that he would correct the mistakes that dogged the Broncos at Seattle and at home against the Texans.

"We have to make sure the communication is clear and concise," Hackett said Monday. "I need to do better at making decisions faster and quicker and getting that information to the quarterback and being on the same page with him. ... It has to improve."

On Thursday, Hackett said some of the operational errors stemmed from having had no prior head coaching experience. Hackett also has two first-time coordinators in Justin Outten on offense and Ejiro Evero on defense.

Hackett was criticized after failing to get calls into his QB fast enough in a 17-16 loss at Seattle in Week 1 when he chose to try a 64-yard field goal (1-in-20 chance) rather than having Wilson go for it on fourth-and-5 (70% chance) in the final minute.

After the operational issues continued in Week 2, when the home crowd resorted to counting down the play clock for the Broncos offense, Hackett huddled with general manager George Paton and told him he'd like to hire a veteran presence to help him manage the game.

He quickly honed in on Rosburg, who has two decades of experience in the NFL. Rosburg was living in Florida following his retirement from the Baltimore Ravens in 2019 after spending 11 seasons as John Harbaugh's special teams coordinator and confidant.

___

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Article Copyright © 2022 The Associated Press, All Rights Reserved.
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